Blar i Bergen Open Research Archive på forfatter "Poovathingal, Suresh K."

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    • New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome 

      Tiraboschi, Ettore; Martina, Silvia; van der Ent, Wietske; Grzyb, Kamil; Gawel, Kinga; Cordero-Maldonado, Maria Lorena; Poovathingal, Suresh K.; Heintz, Sarah; Satheesh, Somisetty Venkata; Brattespe, Jarle; Xu, Ju; Suster, Maximiliano; Skupin, Alexander; Esguerra, Camila V. (Journal article; Peer reviewed, 2020)
      Abstract Objective: To pinpoint the earliest cellular defects underlying seizure onset (epileptogenic period) during perinatal brain development in a new zebrafish model of Dravet syndrome (DS) and to investigate potential ...

    • The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 

      Walter, Jonas; Bolognin, Silvia; Poovathingal, Suresh K.; Magni, Stefano; Gérard, Deborah; Antony, Paul M. A.; Nickels, Sarah L.; Salamanca, Luis; Berger, Emanuel; Smits, Lisa M.; Grzyb, Kamil; Perfeito, Rita; Hoel, Fredrik; Qing, Xiaobing; Ohnmacht, Jochen; Bertacchi, Michele; Jarazo, Javier; Ignac, Tomasz; Monzel, Anna S.; Gonzalez-Cano, Laura; Krüger, Rejko; Sauter, Thomas; Studer, Michèle; Pereira de Almeida, Luis; Tronstad, Karl Johan; Sinkkonen, Lasse; Skupin, Alexander; Schwamborn, Jens C. (Journal article; Peer reviewed, 2021)
      Increasing evidence suggests that neurodevelopmental alterations might contribute to increase the susceptibility to develop neurodegenerative diseases. We investigate the occurrence of developmental abnormalities in ...